ABSTRACT
Background@#Acute glomerulonephritis (AGN) occurs in all age groups and any settings around the world. AGN is a major cause of illness and death in children. However, the signs and symptoms are not specific for the disease.@*Objective@#To study the treatment and outcome of Acute Glomerulonephritis in children, at Pediatric ward, Mahosot Hospital@*Methodology@#A retrospective study was conducted to review the medical records of inpatients admitted to the Pediatric Ward at Mahosot Hospital from January 2014 to January 2017. All patients aged 15 years old or younger with complete medical records were included in the study. The information on signs and symptoms, laboratory results, treatment and outcome of the patients with acute glomerulonephritis were descriptively analyzed and reported.@*Finding@#There were 3,528 patients admitted to the Pediatric Ward at Mahosot Hospital during the three years. Among these, 64 patients were diagnosed as having AGN (1.81%), but only 36 cases met the study inclusion criteria. The proportion of males was slightly higher than females (ratio 1.2:1) with the mean (SD) age of 9.6 (±2.7 years old) years old. More than a half (53.57%) of the patients reported a medical history of pharyngitis or tonsillitis. The most common presenting symptoms and signs were edema (94%), hematuria (25%), anuria (36%) and hypertensive emergency (17%). The key abnormally elevated renal function tests included BUN (44%) and creatinine (28%). The most common complications included hypertensive encephalopathy (25%) and congestive heart failure (8%).@*Conclusion@#AGN is the major cause of acute kidney injury, congestive cardiac failure and hypertensive encephalopathy, which require optimal treatment in order to have a good outcome.
ABSTRACT
Introduction@#Diarrhea is the most common disease of children particularly in those under 5 years old. In Lao PDR, diarrhea is responsible for 12% of all childhood deaths and the disease is increasing. Therefore, there is a need to study optimal disease management in Lao patients@*Methodology@#A retrospective study was carried out by reviewing medical records of patients admitted at the Pediatric Infectious Ward, Mahosot Hospital, Vientiane Capital from 01/01/2017 to 31/06/2018. We included those diagnosed with acute diarrhea aged 15 years old or younger.@*Finding@#Three hundred and seventy children with diarrhea were included in the analyses, with a higher proportion of males than females [230 (62.2%), 140 (37.6%)] with a ratio of 1.6:1. Mean (SD) age of the patients was 2.1±2.33 years old. The most common age group was those < 2 years old with 247 cases (66.8%), followed by the age group of 2-5 years old [92 cases (24.9%)], 5-10 years old [25 cases (6.8%)] and 10-15 years old [6 cases (1.6%)]. The management in patients without clinically-evident dehydration was ORS in 161 (98.7%), IV fluid in 115 (71.5%) and antibotics in 12 (7.4%). For patients with moderate dehydration, the management consisted of giving ORS in 370 (100%), IV fluid in 198 (96%) and antibotics in one (0.5%). One patient with severe dehydration was given ORS and IV fluid.@*Conclusion@#High proportion of diarrhea found in children under 5 years old. Management in patients without clinical dehydration were rehydration with ORS and IV fluid because patients refused to drink ORS.